References

bioph

Biomedical Photonics

2413-9432

Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis

10.24931/2413-9432-2018-7-2-37-49

bioph-235

Research Article

ОБЗОРЫ ЛИТЕРАТУРЫ

LITERATURE REVIEWS

РОЛЬ ФОТОДИНАМИЧЕСКОЙ ТЕРАПИИ В ЛЕЧЕНИИ ПЕРВИЧНЫХ, РЕЦИДИВНЫХ И МЕТАСТАТИЧЕСКИХ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЕЙ ГОЛОВНОГО МОЗГА

THE ROLE OF PHOTODYNAMIC THERAPY IN THE TREATMENT OF PRIMARY, RECURRENT AND METASTATIC MALIGNANT BRAIN TUMORS

Церковский

Д. А.

Tzerkovsky

D. A.

tzerkovsky@mail.ru

Маслаков

Е. А.

Maslakov

E. A.

Багринцев

Д. А.

Bagrintsev

D. A.

Семак

И. А.

Semak

I. A.

Протопович

Е. З.

Protopovich

Yu. L.

Чиж

А. Г.

Chizh

A. G.

Татур

А. А.

Tatur

A. A.

Фоменков

И. С.

Fomenkov

I. S.

Ступак

Д. С.

Stupak

D. S.

Республиканский научно-практический центр онкологии и медицинской радиологии им. Н.Н. АлександроваБеларусьN.N. Alexandrov National Cancer Centre of Belarus,Belarus

2018

25062018

723749

2018

Церковский Д.А., Маслаков Е.А., Багринцев Д.А., Семак И.А., Протопович Е.З., Чиж А.Г., Татур А.А., Фоменков И.С., Ступак Д.С.

Tzerkovsky D.A., Maslakov E.A., Bagrintsev D.A., Semak I.A., Protopovich Y.L., Chizh A.G., Tatur A.A., Fomenkov I.S., Stupak D.S.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.pdt-journal.com/jour/article/view/235

Фотодинамическая терапия является актуальным и перспективным направлением для применения в области клинической нейроонкологии. Применение современных разработок в области лазерных технологий и новых фотосенсибилизаторов позволяет относить данное направление к высокотехнологичным. По данным различных авторов, включение фотодинамической терапии в схемы комбинированного и комплексного лечения пациентов со злокачественными опухолями головного мозга позволяет достигнуть медианы общей выживаемости пациентов от 11 до 26 мес для первичной формы глиобластомы и от 7,5 до 15 мес - для рецидивных форм глиобластомы. Достигнуты определенные результаты в лечении пациентов с метастатическим поражением головного мозга. В данной публикации авторами проанализированы и систематизированы результаты основных клинических исследований в области флуоресцентной диагностики и интраоперационной фотодинамической терапии при первичных, рецидивных и метастатических формах злокачественных новообразований головного мозга.

Photodynamic therapy is a relevant and promising area for research in the field of clinical neuroonocology. Application of modern developments in the field of laser technologies and new photosensitizers allows us to refer to this field as to high-tech. According to various authors, the inclusion of photodynamic therapy in combined and complex treatments of patients with malignant brain tumors allows achieving overall survival median of patients from 11 to 26 months for primary form of glioblastoma, and from 7.5 to 15 months - for recurrent forms of glioblastoma. Certain results have been achieved in the treatment of patients with metastatic brain lesion. In this publication the authors analyzed and systematized the results of the main clinical studies in the field of fluorescent diagnostics and intraoperative photodynamic therapy of primary, recurrent and metastatic forms of malignant brain tumors.

злокачественные опухолиголовной мозгглиомафлуоресцентная диагностикаинтраоперационная фотодинамическая терапия

malignant tumorsbraingliomafluorescence diagnosticsintraoperative photodynamic therapy

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The authors declare that there are no conflicts of interest present.