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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bioph</journal-id><journal-title-group><journal-title xml:lang="ru">Biomedical Photonics</journal-title><trans-title-group xml:lang="en"><trans-title>Biomedical Photonics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2413-9432</issn><publisher><publisher-name>Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24931/2413-9432-2018-7-3-29-35</article-id><article-id custom-type="elpub" pub-id-type="custom">bioph-250</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Биологические материалы в реконструктивной хирургии рака молочной железы</article-title><trans-title-group xml:lang="en"><trans-title>Biological materials in breast cancer reconstructive surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зикиряходжаев</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Zikiryahodjaev</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермощенкова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermoshchenkova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">maryerm@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чиссов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Chissov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Широких</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shirokih</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">МНИОИ им. П.А. Герцена – филиал Национального медицинского исследовательского центра радиологии МЗ РФ;&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова МЗ РФ; &#13;
Российский университет дружбы народов<country>Россия</country></aff><aff xml:lang="en">P.Herzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation; &#13;
The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation; &#13;
Peoples Friendship University of Russia<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">МНИОИ им. П.А. Герцена – филиал Национального медицинского исследовательского центра радиологии МЗ РФ;&#13;
Первый Московский государственный медицинский университет им. И.М. Сеченова МЗ РФ<country>Россия</country></aff><aff xml:lang="en">P.Herzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation; &#13;
The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Российский университет дружбы народов<country>Россия</country></aff><aff xml:lang="en">Peoples Friendship University of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>10</day><month>10</month><year>2018</year></pub-date><volume>7</volume><issue>3</issue><fpage>29</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зикиряходжаев А.Д., Ермощенкова М.В., Чиссов В.И., Широких И.М., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Зикиряходжаев А.Д., Ермощенкова М.В., Чиссов В.И., Широких И.М.</copyright-holder><copyright-holder xml:lang="en">Zikiryahodjaev A.D., Ermoshchenkova M.V., Chissov V.I., Shirokih I.M.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pdt-journal.com/jour/article/view/250">https://www.pdt-journal.com/jour/article/view/250</self-uri><abstract><p>В настоящее время реконструктивно-пластические операции становятся стандартным вариантом при хирургическом и комбинированном лечении больных раком молочной железы (РМЖ). При одномоментной реконструкции молочной железы актуальным становится применение биологических имплантатов, способных заменить мышечные аутотрансплантаты и, следовательно, сократить травматичность, кровопотерю и время операции, а также избежать дефектов донорских зон. С 2014 по 2017 гг. в МНИОИ им. П.А. Герцена выполнена 151 реконструктивная операция у 121 больной РМЖ (средний возраст 41,5 лет) с применением синтетических и биологических материалов. 0 стадия РМЖ TisN0M0 была диагностирована у 11 (9,1%) больных, I стадия – у 52 (42,9%), IIA– у 41 (33,9%), IIB – у 9 (7,4%), IIIA — у 4 (3,3%), IIIB – у 2 (1,7%), IIIC – у 2 (1,7%). С целью укрепления нижнего склона в 34 случаях был использован биологический имплантат — ацеллюлярный дермальный матрикс Permacol. Отличные косметические результаты отмечены в 20 (58,9%) случаях, хорошие – в 11 (32,3%), неудовлетворительные – в 3 (8,8%). Биологические материалы являются важным дополнением к различным вариантам реконструкции молочной железы. Критерием выбора материала для укрепления нижнего склона молочной железы при подкожной или кожесохранной мастэктомии по поводу рака с одномоментной реконструкцией силиконовым эндопротезом является величина pinch-теста.</p></abstract><trans-abstract xml:lang="en"><p>Currently, reconstructive-plastic surgery is becoming the standard for surgical and combined treatment of breast cancer (BC) patients.</p><p>With a one-stage reconstruction of the breast, the use of biological implants that can replace muscle autografts and, consequently, reduce trauma, blood loss and operation time, and also to avoid defects in the donor zones is becoming topical. From 2014 to 2017, 151 reconstructive operations on 121 patients with BC (average age 41.5 years) using synthetic and biological materials were carried out in P.Herzen Moscow Oncology Research Institute. 0 stage of BC TisN0M0 was diagnosed in 11 (9.1%) patients, I stage – in 52 (42.9%), IIA – in 41 (33.9%), IIB – in 9 (7.4%), IIIA – in 4 (3.3%), IIIB – in 2 (1.7%), IIIC – in 2 (1.7%). To strengthen the lower slope, a biological implant – Permacol acellular dermal matrix, was used in 34 cases. Cosmetic result was rated as excellent in 20 (58.9%) cases, good in 11 (32.3%), unsatisfactory in 3 (8,8%). Biological materials are an important addition to various options for breast reconstruction. The criterion for selecting the material for strengthening the lower slope of the breast with subcutaneous or cutaneous mastectomy for cancer with a one-stage reconstruction using a silicone endoprosthesis is the pinch-test value.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>реконструктивные операции при раке молочной железы</kwd><kwd>ацеллюлярный дермальный матрикс</kwd><kwd>биологический имплантат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>breast cancer reconstructive surgery</kwd><kwd>acellular dermal matrix</kwd><kwd>biological implant</kwd><kwd>biological implant</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Асеев А.В. Психологические проблемы, связанные с раком молочной железы // Клиническая медицина. – 1993. – № 3. – С. 30–34.</mixed-citation><mixed-citation xml:lang="en">Аseev А.V. 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