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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bioph</journal-id><journal-title-group><journal-title xml:lang="ru">Biomedical Photonics</journal-title><trans-title-group xml:lang="en"><trans-title>Biomedical Photonics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2413-9432</issn><publisher><publisher-name>Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24931/2413-9432-2019-8-3-43-45</article-id><article-id custom-type="elpub" pub-id-type="custom">bioph-349</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE-REPORTS</subject></subj-group></article-categories><title-group><article-title>Эффективность фотодинамической терапии больной ранним центральным раком лёгкого и муковисцидозом</article-title><trans-title-group xml:lang="en"><trans-title>Effectiveness of photodynamic therapy of a patient with early central lung cancer and cystic fibrosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борзенко</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Borzenko</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Благовещенск</p></bio><bio xml:lang="en"><p>Blagoveshchensk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Решетов</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Reshetov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фатьянова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Fatyanova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Огданская</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ogdanskaya</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">ksenia28r@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гафаров</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Gafarov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романко</surname><given-names>Ю. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanko</surname><given-names>Yu. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Амурская государственная медицинская академия<country>Россия</country></aff><aff xml:lang="en">Amur State Medical Academy<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Первый МГМУ им. И.М. Сеченова (Сеченовский Университет)<country>Россия</country></aff><aff xml:lang="en">Sechenov First Moscow State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Первый МГМУ им. И.М. Сеченова (Сеченовский Университет), Москва;  МРНЦ им. А.Ф. Цыба – филиал ФГБУ «НМИЦ радиологии» Минздрава России, Обнинск<country>Россия</country></aff><aff xml:lang="en">Sechenov First Moscow State Medical University, Moscow; A. Tsyb Medical Radiological Research Centre – branch of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation (A. Tsyb MRRC), Obninsk<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>19</day><month>10</month><year>2019</year></pub-date><volume>8</volume><issue>3</issue><fpage>43</fpage><lpage>45</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Борзенко Е.С., Решетов И.В., Фатьянова А.С., Огданская К.В., Гафаров М.М., Романко Ю.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Борзенко Е.С., Решетов И.В., Фатьянова А.С., Огданская К.В., Гафаров М.М., Романко Ю.С.</copyright-holder><copyright-holder xml:lang="en">Borzenko E.S., Reshetov I.V., Fatyanova A.S., Ogdanskaya K.V., Gafarov M.M., Romanko Y.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pdt-journal.com/jour/article/view/349">https://www.pdt-journal.com/jour/article/view/349</self-uri><abstract><p>Авторы описывают клиническое наблюдение с полным клиническим эффектом после многокурсовой фотодинамической терапии больной центральным раком легких и муковисцидозом с использованием фотодитазина. Фотодитазин вводили внутривенно в дозе 0,8 мг/кг за 2 ч до проведения сеанса облучения. Параметры облучения: плотность мощности – 150 мВт/см2, плотность энергии – 200 Дж/см2. Всего было проведено 3 курса фотодинамической терапии. В результате проведенного лечения отмечена полная регрессия опухоли. Пациентка находится под динамическим наблюдением в течение 2 лет после лечения, рецидива не выявлено.</p></abstract><trans-abstract xml:lang="en"><p>The authors describe a clinical observation with full clinical effect after multi-course photodynamic therapy of a patient with central lung cancer and cystic fibrosis using Photoditazine. Photoditazine was administered intravenously at a dose of 0.8 mg/kg 2 hours before the irradiation session. Irradiation parameters: power density – 150 mW/cm2, energy density – 200 J/cm2. In total, 3 courses of photodynamic therapy were performed. As a result of the treatment, a complete regression of the tumor was noted. The patient has been under dynamic observation for 2 years after treatment, no relapse was observed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фотодинамическая терапия</kwd><kwd>фотодитазин</kwd><kwd>центральный рак лёгкого</kwd><kwd>муковисцидоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>photodynamic therapy</kwd><kwd>photoditazine</kwd><kwd>central lung cancer</kwd><kwd>cystic fibrosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Злокачественные новообразования в России в 2017 году (заболеваемость и смертность) / под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. – М.: МНИОИ и. П.А. 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