biophBiomedical PhotonicsBiomedical Photonics2413-9432Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis10.24931/2413-9432-2020-9-1-27-33bioph-402Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESИспользование контрастного усиления при ультразвуковом исследовании простых и сложных кист почекThe use of contrast enhancement in the diagnosis of simple and complex cysts kidneysСоловьевЯ. А.SolovievYa. A.

Москва

Moscow

yan.solovev@mail.ruМитинаЛ. А.MitinaL. A.

Москва

Moscow

АлексеевБ. Я.AlekseevB. Ya.

Москва

Moscow

СтепановС. О.StepanovS. O.

Москва

Moscow

КалпинскийА. С.KalpinskiyA. S.

Москва

Moscow

ДимитровВ. О.DimitrovO. V.

Москва

Moscow

НазойкинЕ. А.NazoikinE. A.

Москва

Moscow

МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава РФРоссияP.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of RussiaRussian FederationМосковский государственный университет пищевых производствРоссияMoscow State University of Food ProductionRussian Federation202023042020912733Copyright © Соловьев Я.А., Митина Л.А., Алексеев Б.Я., Степанов С.О., Калпинский А.С., Димитров В.О., Назойкин Е.А., 20202020Соловьев Я.А., Митина Л.А., Алексеев Б.Я., Степанов С.О., Калпинский А.С., Димитров В.О., Назойкин Е.А.Soloviev Y.A., Mitina L.A., Alekseev B.Y., Stepanov S.O., Kalpinskiy A.S., Dimitrov O.V., Nazoikin E.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.pdt-journal.com/jour/article/view/402

В развитых странах основными методами исследования и динамического наблюдения за кистозными образованиями почек являются КТ и МРТ, однако их применение невозможно у пациентов с тяжелыми сопутствующими заболеваниями, а также при наличии в организме металлоконструкций, кардиостимуляторов и т.д. Дополнительно принимая во внимание высокую дозу лучевой нагрузки при использовании КТ, получаемой пациентом при динамическом наблюдении, является актуальной разработка альтернативных методик. К относится ультразвуковое исследование с применением контрастного усиления (КУУЗИ), которое может использоваться как альтернативный или дополнительный метод в первичной диагностике или в динамическом наблюдении кистозных образований почек. В статье авторы приводят собственный опыт применения при ультразвуковом исследовании контрастного препарата для диагностики и динамического наблюдения сложных кист почек, а также внедрения этой технологии для распределения пациентов по классификации M.A. Bosniak.

В основу исследования вошли результаты применения КУУЗИ у 28 пациентов с различными кистозными образованиями почек. Предварительно пациенты были разделены на две группы: первую составили 13 пациентов с простыми кистами, вторую – 15 пациентов с подозрением на сложные кисты. В результате исследования было получено следующее распределение пациентов по М.А. Bosniak: 15 отнесены к I категории, 7 – ко II, 3 – к III, 3 – к IV. Исследуемый метод КУУЗИ отличается простотой и эффективностью. Специфичность метода составила 78,57%, точность метода – 85,71%, прогностичность положительного результата – 81,25%, прогностичность отрицательного результата – 91,66%. КУУЗИ помогает быстро и качественно провести дифференциальную диагностику между простой кистой и сложной, а также классифицировать кисты по M.A. Bosniak.

In developed countries, the main methods of research and dynamic monitoring of cystic kidney formations are CT and MRI, but their use is impossible in patients with severe concomitant diseases, as well as in the presence of metal structures, pacemakers, etc. Additionally, taking into account the high dose of radiation exposure when using CT obtained by the patient during dynamic observation, the development of alternative methods is relevant. These include, but not limited to, ultrasound using contrast enhancement, which can be used as an alternative or additional method in primary diagnosis or in the dynamic observation of cystic kidney formations. In the article, the authors provide their own experience with the use of an ultrasound contrast medium for the diagnosis and dynamic observation of complex kidney cysts, as well as the introduction of ultrasound observation using a contrast medium to classify patients according to Bosniak M.A.

The study included the results of the use of contrast enhanced ultrasound (CEUS) in 28 patients with various cystic formations of the kidneys. The patients were previously divided into two groups: the first consisted of 13 patients with simple cysts, the second – 15 with suspected complex cysts. As a result of the study, the patients were distributed as follows: 15 patients were classified as Bosniak type I, 7 patients – as type II, 3 - type III, 3 - type IV. The studied CEUS method is simple and effective. The specificity of the method was 78.57%, the accuracy of the method was 85.71%, the predictive value of the positive result was 81.25%, and the predictive value of the negative result was 91.66%. CEUS helps to quickly and accurately conduct differential diagnosis between a simple cyst and a complex one, as well as classify cysts according to M.A. Bosniak.

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The authors declare that there are no conflicts of interest present.