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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">bioph</journal-id><journal-title-group><journal-title xml:lang="ru">Biomedical Photonics</journal-title><trans-title-group xml:lang="en"><trans-title>Biomedical Photonics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2413-9432</issn><publisher><publisher-name>Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24931/2413-9432-2022-11-2-33-38</article-id><article-id custom-type="elpub" pub-id-type="custom">bioph-541</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE-REPORTS</subject></subj-group></article-categories><title-group><article-title>Возможности применения пероральной внутрипросветной лазерной литотрипсии при крупном конкременте общего желчного протока (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Opportunities of using oral intraluminal laser lithotripsy for a large calculus of the common bile duct (clinical report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>Y. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow </p></bio><email xlink:type="simple">ivanovkb83@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сазонов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sazonov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамошин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamoshin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p><p>Орел</p></bio><bio xml:lang="en"><p>Oryol</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow </p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панченков</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Panchenkov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow </p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА России; Московский государственный медико-стоматологический университет им. А.И. Евдокимова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Scientific and Clinical Center of Specialized Types of Medical Care and Medical Technologies of the FMBA of Russia; Moscow State University of Medicine and Dentistry named after A.I. Evdokimov” of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Scientific and Clinical Center of Specialized Types of Medical Care and Medical Technologies of the FMBA of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Орловская областная клиническая больница; Орловский государственный университет имени И.С. Тургенева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Oryol Regional Clinical Hospital; Orel State University named after I.S. Turgenev</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Государственный научный центр лазерной медицины им. О.К. Скобелкина ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Skobelkin State Scientific Center of Laser Medicine FMBA</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет им. А.И. Евдокимова; Государственный научный центр лазерной медицины им. О.К. Скобелкина ФМБА России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry named after A.I. A.I. Evdokimov of the Ministry of Health of Russia; Skobelkin State Scientific Center of Laser Medicine FMBA</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>27</day><month>07</month><year>2022</year></pub-date><volume>11</volume><issue>2</issue><fpage>33</fpage><lpage>38</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванов Ю.В., Сазонов Д.В., Смирнов А.В., Мамошин А.В., Баранов А.В., Панченков Д.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Иванов Ю.В., Сазонов Д.В., Смирнов А.В., Мамошин А.В., Баранов А.В., Панченков Д.Н.</copyright-holder><copyright-holder xml:lang="en">Ivanov Y.V., Sazonov D.V., Smirnov A.V., Mamoshin A.V., Baranov A.V., Panchenkov D.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.pdt-journal.com/jour/article/view/541">https://www.pdt-journal.com/jour/article/view/541</self-uri><abstract><p>Представлено клиническое наблюдение успешного выполнения пероральной внутрипросветной лазерной литотрипсии с последующей литоэкстракцией крупного конкремента общего желчного протока у пациентки с холедохолитиазом и механической желтухой. Для проведения внутрипротоковой литотрипсии использовали тулиевый лазер «Уролаз» в следующих режимах: энергия – 0,025-0,05-0,1 Дж, максимум до 0,5 Дж. Средняя мощность 6-10 Вт. Лазерное воздействие проводили импульсами в водной среде с целью профилактики карбонизации волокна световода и задымления. Эффект воздействия на конкремент проявлялся в его фрагментации и образовании мелких частиц без повреждения слизистой оболочки общего желчного протока. Общая продолжительность вмешательства составила 45 мин. Метод является эффективным и безопасным, позволяет избежать необходимости выполнения эндоскопической папиллосфинктеротомии и нарушения анатомической целостности и физиологической функции сфинктера Одди.</p></abstract><trans-abstract xml:lang="en"><p>There is a clinical report of successful oral intraluminal laser lithotripsy with subsequent lithoextraction of a large concretion of the common bile duct in a patient with choledocholithiasis and mechanical jaundice. For the intraluminar lithotripsy a tulium laser "Urolaz" was used with energy modes 0,025-0,05-0,1 J, up to a maximum of 0.5 J. The average power is 6-10 W. Laser exposure was carried out by pulses in an aqueous medium in order to prevent carbonation of the light guide and smoke. The effect of exposure to the concretion was manifested in its fragmentation and the formation of small particles without damage of the mucous membrane of the common bile duct. The total duration of the intervention was 45 minutes. The method is effective and safe, thus it avoids the need of endoscopic papillosphincterotomy and violation of the anatomical integrity and physiological function of the Oddi sphincter.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>холедохолитиаз</kwd><kwd>папиллосфинктеротомия</kwd><kwd>фрагментация конкремента</kwd><kwd>эндоскопическая лазерная литотрипсия</kwd><kwd>общий желчный проток</kwd></kwd-group><kwd-group xml:lang="en"><kwd>choledocholithiasis</kwd><kwd>papillosphincterotomy</kwd><kwd>fragmentation of concretion</kwd><kwd>endoscopic laser lithotripsy</kwd><kwd>common bile duct</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gutierrez O.I., Bekkali N.L.H., Raijman I., Sturgess R., Sejpal D.V., Aridi H.D. Efficacy and Safety of Digital Single-Operator Cholangioscopy for Difficult Biliary Stones // Clin. Gastroenterol. 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