PHOTODYNAMIC THERAPY FOR RESISTANT FOREHEAD KERATOACANTHOMA
https://doi.org/10.24931/2413-9432-2016-5-4-44-47
Abstract
The results of the follow-up of the patient with persistent forehead keratoacanthoma are represented. The patient underwent one course of PDT with intralesional administration of photosensitizer radachlorin at a dose of 0.75 ml/cm2 of tumor. The characteristics of the irradiation were as follows: the laser power density 0.39 W/cm2, the light dose – 300 J/cm2. Two weeks after treatment there was a cosmetically satisfying soft normotrophic scar with no attachment to underlying tissues in the site of the treatment. According to cytological study tumor cells were not detected. For one-year follow-up there was no recurrence.
About the Author
S. D. DibirovaRussian Federation
Moscow, Russia
References
1. Kaplan M.A., Nikitina R.G., Romanko Yu.S., Bozadzhiev L.L., Malygina A.I., Drozhzhina V.V. Photodynamic therapy sarcoma M-1 in experimental animals, Lazernaya meditsina, 1998, Vol. 2, No. 2-3, pp. 38-42. (in Russian).
2. Yaroslavtseva-Isaeva E.V., Kaplan M.A., Romanko Yu.S., Sokol N.I. Development of the method of photodynamic therapy for experimental tumor (sarcoma M-1) with local administration of photosensitizer, Rossiiskii bioterapevticheskii zhurnal, 2003. – Vol. 2, No. 4, pp. 19-22. (in Russian).
3. Kaplan M.A., Romanko Yu.S., Popuchiev V.V., Yuzhakov V.V., Bandurko L.N. Morphofunctional features of sarcoma M-1 in photodynamic therapy using a photosensitizer photodithazine, Rossiiskii bioterapevticheskii zhurnal, 2004, Vol. 3, No. 2, p. 52. (in Russian).
4. Romanko Yu.S., Tsyb A.F., Kaplan M.A., Popuchiev V.V. Impact of photodynamic therapy using photoditazin on the morphofunctional characteristics of sarcoma M-1, Byulleten' eksperimental'noi biologii i meditsiny, 2004, Vol. 138, No. 12, pp. 658-664. (in Russian).
5. Kaplan M.A., Romanko Yu.S., Mardynskaya V.P., Malygina A.I., Burmistrova N.V., Yaroslavtseva-Isaeva E.V., Spichenkova I.V. Development of a method of photodynamic therapy with photoditazin in experimental animals with sarcoma M-1, Rossiiskii bioterapevticheskii zhurnal, 2004, Vol. 3, No. 2, p. 52. (in Russian).
6. Kaplan M.A., Romanko Yu.S., Popuchiev V.V., Yuzhakov V.V., Bandurko L.N., Mikhina L.N., Fomina N.K., Malygina A.I., Ingel' I.E. Effect of light energy density on the antitumor efficacy of photodynamic therapy with photodithazine, Lazernaya meditsina, 2005, Vol. 9, No. 2, pp. 46-54. (in Russian).
7. Kaplan M.A., Galkin V.N., Romanko Yu.S., Osipchuk Yu.S., Drozhzhina V.V., Malova T.I., Ol'shevskaya V.A. Study of effectiveness of photodynamic therapy for PC-1 experimental tumors with a liposomal photosensitizer chlorine e6 boronated, Radiatsiya i Risk, 2016, Vol. 25, No. 3, pp. 57-65. (in Russian).
8. Sun M., Zhou C., Zeng H, Puebla-Osorio N., Damiani E., Chen J., Wang H., Li G., Yin F., Shan L., Zuo D., Liao Y., Wang Z., Zheng L., Hua Y., Cai Z. Hiporfin- mediated photodynamic therapy in preclinical treatment of osteosarcoma, Photochem Photobiol., 2015, Vol. 91(3), pp. 533-544.
9. Zeng H., Sun M., Zhou C., Yin F., Wang Z., Hua Y., Cai Z. Hematoporphyrin monomethyl ether-mediated photodynamic therapy selectively kills sarcomas by inducing apoptosis, PLoS One, 2013, Vol. 8(10), e77727.
10. Xue J., Li C., Liu H., Wei J., Chen N., Huang J. Optimal light dose and drug dosage in the photodynamic treatment using PHOTOCYANINE, Photodiagnosis Photodyn Ther, 2011, Vol. 8(3), pp. 267-274.
11. Castano A.P., Mroz P., Wu M.X., Hamblin M.R. Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model, Proc Natl Acad Sci USA, 2008, Vol. 105(14), pp. 5495-5500.
12. Kuznetsov V.V. Application of photodynamic therapy in the national oncology (review of literature), Issledovaniya i praktika v meditsine, 2015, Vol. 2, No. 4, pp. 98-105. (in Russian).
13. Kapinus V.K., Romanko Yu.S., Kaplan M.A., Ponomarev G.V., Sokol N.I. The efficacy of fluorescence diagnostics and photodynamic therapy with photosensitizer photodithazine in patients with skin cancer Эффективность флюоресцентной диагностики и фотодинамической терапии с фотосенсибилизатором фотодитазин у больных раком кожи, Rossiiskii bioterapevticheskii zhurnal, 2005, Vol. 4, No. 3, pp. 69-75. (in Russian).
14. Katsalap S.N., Romanko Yu.S. Photodynamic therapy of recurrent basal cell carcinoma, Vestnik esteticheskoi meditsiny, 2012, Vol. 11, No. 1, pp. 44-48. (in Russian).
15. Kaplan M.A., Romanko Yu.S. Photodynamic therapy as a new definitive method of treatment in patients with recurrent tumors of "uncomfortable" sites, Voprosy onkologii, 2000, Vol. 46, No. 2, pp. 238. (in Russian).
16. Sukhova T.E., Romanko Yu.S., Yaroslavtseva-Isaeva E.V., Korenev S.V., Prokof'ev A.A. Interstitial mode of photosensitizer injection for photodynamic therapy for basal cell carcinoma, Rossiiskii zhurnal kozhnykh i venericheskikh boleznei, 2010, No. 2, pp. 4-10. (in Russian).
17. Molochkov A.V., Sukhova T.E., Tret'yakova E.I., Akopova K.V., Koroleva L.P., Prokof'ev A.A., Rumyantsev S.A., Alieva P.M., Romanko Yu.S., Molochkov V.A. Comparative evaluation of the efficiency of laserinduced thermotherapy and photodynamic therapy for superficial and micronodular basalomas, Rossiiskii zhurnal kozhnykh i venericheskikh boleznei, 2012, No. 4, pp. 30-36. (in Russian).
18. Romanko Yu.S., Kaplan M.A., Ivanov S.A., Galkin V.N., Molochkova Yu.V., Kuntsevich Zh.S., Tret'yakova E.I., Sukhova T.E., Molochkov V.A., Molochkov A.V. Efficacy of photodynamic therapy for basal cell carcinoma using photosensitizers of different classes, Voprosy onkologii, 2016, No. 3, pp. 447-450. (in Russian).
19. Fargnoli M.C., Peris K. Photodynamic therapy for basal cell carcinoma, Future Oncol, 2015, Vol. 11(22), pp. 2991-2996.
20. Sukhova T.E., Molochkov V.A., Romanko Yu.S., Changlyan K.A., Tret'yakova E.I. Photodynamic therapy for actinic keratosis with topical application of the photosensitizer photoditasine, Rossiiskii zhurnal kozhnykh i venericheskikh boleznei, 2010, No. 5, pp. 4-8. (in Russian).
21. Sukhova T.E., Changlyan K.A., Molochkov A.V., Molochkov V.A., Korenev S.V., Kuntsevich Zh.S., Molochkova Yu.V., Galkin V.N., Romanko Yu.S. Comparative studies of efficacy of photodynamic therapy and kryotherapy for treatment of actinic keratosis, Biomedical Photonics, 2016, Vol. 5, No. 3, pp. 19-29. (in Russian).
22. Kessels J.P., Nelemans P.J., Mosterd K., Kelleners-Smeets N.W., Krekels G.A., Ostertag J.U. Laser-mediated Photodynamic Therapy: An Alternative Treatment for Actinic Keratosis?, Acta Derm Venereol, 2016, Vol. 96(3), pp. 351-354.
23. Galkin V.N., Molochkov A.V., Molochkov V.A., Korenev S.V., Sukhova T.E., Kuntsevich Zh.S., Romanko Yu.S. Photodynamic therapy of condylomata acuminate, Issledovaniya i praktika v meditsine, 2016, Vol. 3, No. 2, pp. 66-70. (in Russian).
24. Kacerovska D., Pizinger K., Kumpova M., Cetkovska P. Genital warts treated by photodynamic therapy, Skinmed, 2007, Vol. 6(6), pp. 295- 297.
25. Molochkov V.A., Molochkov A.V., Sukhova T.E., Khlebnikova A.N., Kuntsevich Zh.S., Romanko Yu.S., Dibirova S.D., Bochkareva E.V. Local photodynamic therapy for keratoacanthoma, Rossiiskii zhurnal kozhnykh i venericheskikh boleznei, 2012, No. 4, pp. 21-24. (in Russian).
26. Molochkova Yu.V., Kuntsevich Zh.S., Sukhova T.E., Dibirova S.D., Galkin V.N., Ivanov S.A., Romanko Yu.S. Photodynamic therapy of typical and atypical keratoacanthoma, Al'manakh klinicheskoi meditsiny, 2016, Vol. 44, No. 1, pp. 64-70. (in Russian).
27. Galkin V.N., Romanko Yu.S., Kaplan M.A., Molochkov A.V., Molochkov V.A., Kuntsevich Zh.S., Sukhova T.E., Dibirova S.D. The use of photodynamic therapy in the treatment of keratoacantohomas, Biomedical Photonics, 2016, Vol. 5, No. 2, pp. 21-25. (in Russian).
Review
For citations:
Dibirova S.D. PHOTODYNAMIC THERAPY FOR RESISTANT FOREHEAD KERATOACANTHOMA. Biomedical Photonics. 2016;5(4):44-47. (In Russ.) https://doi.org/10.24931/2413-9432-2016-5-4-44-47