Specialized medical care for patients with malignant neoplasms of the maxillofacial area in the Penza region of Russia
https://doi.org/10.24931/2413-9432-2021-10-3-23-31
Abstract
This article analyzes domestic and foreign sources, regulatory documents of the Russian Federation, in order to determine the etiological factors of oral cancer, assess the statistical data on morbidity and mortality from malignant neoplasms of the maxillofacial region in the Penza region. The results of changing the routing, an interdisciplinary approach to treating patients with malignant neoplasms of the maxillofacial region in the Penza region are presented. The epidemiology, clinical manifestations, main diagnostic methods, routing, treatment and rehabilitation of patients with head and neck oncology are considered. The results of treatment of patients with oral cavity and lower lip cancer using photodynamic therapy (PDT), both alone and in combination with radiation and chemotherapy, are analyzed. The study showed that PDT of tumors of the lower lip and buccal mucosa in mono-mode made allowed achieving 100% efficiency. After the completed treatment, all participants in the experiment were provided with a complex of rehabilitation, including nutritional support, psychological assistance, exercise therapy, training in correct swallowing tactics, percutaneous endoscopic gastrostomy, and a course of oral cavity massage. An interdisciplinary approach to treating malignant neoplasms of the maxillofacial region is the most correct in modern practice.
About the Authors
M. V. Lebedev
Penza State University
Russian Federation
Russian Federation
Penza
Yu. A. Abdullina
Kazan State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Kazan
I. Yu. Zakharova
Penza State University
Russian Federation
Russian Federation
Penza
References
1. Order of the Ministry of Health of Russia № 48n «On Amendments to the Procedure for Providing Medical Care to the Population in the Profile of «Oncology» dated 05.02.2019, approved by Order of the Ministry of Health of the Russian Federation dated November 15, 2012 № 915n». (in Russian)
2. Russian statistical yearbook. Federal State Statistics Service, 2018. (in Russian)
3. Chissova V. I. Diagnostics and treatment of malignant neoplasms. Clinical protocols – MNIOI after P. A. Herzen a brach of the federal State Budgetary Institution «NMIRTS» of the Russia Federation Publ., 2013, p. 599. (in Russian)
4. Decree of the Government of the Penza region of June 25, 2019 No. 370 pp «On approval of the regional program «Fight against cancer in the Penza region»». (in Russian)
5. Kaprin A. D., Starinskiy V. V., Petrova G. V. Malignant neoplasms in Russia in 2018 (morbidity and mortality) – MNIOI after P. A. Herzen a brach of the federal State Budgetary Institution «NMIRTS» of the Russia Federation Publ., 2019, p. 250. (in Russian)
6. Mikhalchenko D. V., Zhidovinov A. V. Types of malignant neoplasms of the maxillofacial region and modern methods of treatment. Modern problems of science and education., 2016, vol. 6. (in Russian)
7. Jiang X., Wu J., Wang J, Huang R. Tobacco and oral squamous cell carcinoma: A review of carcinogenic pathways. Tobacco induced disease, 2019, p.17–29.
8. Zharikov K. M., Nafikov A. V., Astafiev B. V. Factors causing diseases of the oral cavity. Bulletin of medical Internet conferences, 2019, vol. 9 (5), p. 202.
9. Kolenko Yu. G. The role of risk factors in the development of precancerous diseases of the mucous membrane of the cavity. Modern dentistry, 2016, vol. 1 (80), p. 53. (in Russian)
10. Lebedev M. V., Zakharova I.Yu. Disability of the population due to the postponed malignant processes of the maxillofacial region. Ural Medical Journal, 2020, vol. 6 (189), p. 180–185. (in Russian)
11. Pisny I. V. Cancer of the tongue: surgical treatment. Izvestiya Samara Scientific Center of the Russian Academy of Sciences, 2015, vol. 17, No. 2 (3), pp. 633–637. (in Russian)
12. Efretov V. M., Dylenok I. N. Comparative evaluation of the effectiveness of neoadjuvant chemotherapy and preoperative radiation therapy in the large fractionation mode in the treatment of patients with stage II – III breast cancer. Oncology, 2006, vol.8 (1), pp. 54–60. (in Russian)
13. O’Sullivan B., Davis A. M., Turcotte R. et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomized trial. Lancet, 2017, vol. 359, p. 2235.
14. Sokolov V. V., Chisov V. I., Filonenko E. V., Kozlov D. N., Smirnov V. V. Photodynamic therapy of cancer with the photosensitizer PHOTOGEM. Proceedings of SPIE – The International Society for Optical Engineering, 1995, Vol. 2325, Р. 367–374.
15. Filonenko E. V. The history of development of fluorescence diagnosis and photodynamic therapy and their capabilities in oncology. Russian Journal of General Chemistry, 2015, Vol. 85 (1), Р. 211–216.
16. Sokolov V. V., Filonenko E. V., Telegina, L. V., Boulgakova N. N., Smirnov V. V. Combination of fluorescence imaging and local spectrophotometry in fluorescence diagnostics of early cancer of larynx and bronchi. Quantum Electronics, 2002, Vol. 32 (11), Р. 963–969.
17. Sokolov V. V., Chissov V. I., Filonenko, E. V., Kozlov D. N., Smirnov V. V. First clinical results with a new drug for PDT. Proceedings of SPIE – The International Society for Optical Engineering, 1995, Vol. 2325, Р. 364–366.
Review
For citations:
Lebedev M.V., Abdullina Yu.A., Zakharova I.Yu. Specialized medical care for patients with malignant neoplasms of the maxillofacial area in the Penza region of Russia. Biomedical Photonics. 2021;10(3):23-31. https://doi.org/10.24931/2413-9432-2021-10-3-23-31
Views:
620
Email this article 