A case-report of successful photodynamic therapy of the patient with severe vulvar dysplasia
Abstract
A case of successful photodynamic therapy (PDT) of the patient with grade 3 vulvar dysplasia. One course of treatment with photolon was performed. The photosensitizer was administered intravenously as 30 min infusion in dose of 1.0 mg/kg body weight. The PDT session was performed 3h after infusion of photolon, the light dose was 350 J/cm2. The treatment was well tolerated. Due to PDT a complete tumor regression was achieved. The patient received a strict follow-up schedule, for 8 months after PDT no recurrence was observed.
About the Authors
E. V. Filonenko
P.A. Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
L. G. Serova
P.A. Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
References
1. Kaprin A.D., Starinskiy V.V., Petrova G.V. Zlokachestvennye novoobrazovaniya v Rossii v 2012 godu (zabolevaemost' i smertnost') (Malignant neoplasms in Russia in 2012 (incidence and mortality)). M. – 2014.
2. Ashrafyan L.A., Kostava M.M., Kharchenko N.V. Zabolevaniya sheiki matki, vlagalishcha i vulvy (Diseasesof cervix, vagina and vulva), M. 2003, pp. 346–366.
3. Sdvizhkov A.M. Filinov V.L., Sokolov V.V. FDT v lechenii predrakovykh zabolevaniy i rannego raka vulvy. Posobie dlya vrachei (PDT in treating pre-cancer and early cancer of vulva. Textbook for physicians). М. 2008.
4. Chulkova O.V., Novikova E.G., Chulkova E.A., Sokolov V.V. Diagnostika I lechenie fonovykh i predrakovykh zabolevaniy vulvy (Diagnosis and treating background and pre-cancer diseases of vulva) // Prakticheskaya onkologiya, Т.7, № 4–2006, pp. 197–204.
5. Olejek A., Rembielak-Stawecka B «Photodynamic diagnosis and therapy in gynecology» // Gynecol Pol. 2004 Mar; 75 (3): 228–43.
6.
Review
For citations:
Filonenko E.V., Serova L.G. A case-report of successful photodynamic therapy of the patient with severe vulvar dysplasia. Photodynamic therapy and photodyagnosis. 2014;3(4):31-33. (In Russ.)
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