Photodynamic therapy of basal cell carcinoma of the face H-zone
https://doi.org/10.24931/2413-9432-2025-14-2-27-30
Abstract
This article reviews clinical experience in treating skin neoplasms using photodynamic therapy with combined ultrasound and fluorescence diag- nostics for neoplasms in the nose, lateral face, and adjacent areas. Injectable forms of chlorine-type drugs were used as photosensitizers – photodi- tazine or photoran at a dose of 0.7 to 2.5 mg per kilogram of patient body weight. The drug was administered intravenously for 30 minutes 2.5-3.0 hours before tumor irradiation. Of 107 observations over a 9-month observation period, one case of marginal tumor recurrence in the treatment area was detected. Thus, the recurrence rate was 0.93%. The results show that three-dimensional tumor visualization for the H-zone with complex noninvasive diagnostics allows achieving high efficiency in photodynamic therapy of non-melanoma tumors of the above anatomical localizations.
About the Authors
E. V. Nadkernichnaya
State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital
of the Moscow City Healthcare Department”
Russian Federation
Russian Federation
Moscow
M. V. Ermoschenkova
State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital
of the Moscow City Healthcare Department”; First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
Moscow
V. E. Semin
State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital
of the Moscow City Healthcare Department”
Russian Federation
Russian Federation
Moscow
S. A. Parts
State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital
of the Moscow City Healthcare Department”
Russian Federation
Russian Federation
Moscow
V. N. Galkin
State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital
of the Moscow City Healthcare Department”
Russian Federation
Russian Federation
Moscow
I. V. Reshetov
First Moscow State Medical University named after I.M. Sechenov
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Nadkernichnaya E.V., Ermoschenkova M.V., Semin V.E., Parts S.A., Galkin V.N., Reshetov I.V. Photodynamic therapy of basal cell carcinoma of the face H-zone. Biomedical Photonics. 2025;14(2):27–30. https://doi.org/10.24931/2413-9432-2025-14-2-27-30
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