CLINICAL PROBLEMS OF DIRECT DOSIMETRY (IN VIVO) IN CONTACT RADIATION THERAPY
https://doi.org/10.24931/2413-9432-2018-7-2-19-24
Abstract
The use of multicomponent methods of special treatment (surgery, polychemotherapy, radiation therapy, laser photodynamic therapy) in oncology requires the control of doses in the tumor and healthy organs with high accuracy. A method of direct dosimetry using fiber-optic scintillation dosimeter MCD-4 is proposed. The dosimeter is fixed on endostats and is visualized on CT/MRI. The coordinates are entered into the anatomical units and dosimetry calculations, the data are mapped, the doses are adjusted on medical grounds. The developed technique of direct dosimetry allows monitoring of the contact radiation therapy (CRT) procedure in real time and making the necessary changes and corrections during the treatment. The refinement of the absorbed dose values using calculations and direct dosimetry minimizes the risk of complications and ensures the possibility of effective use of other treatment methods, including photodynamic therapy, after CRT.
About the Authors
V. A. Titova
Russian Scientific Center of Roentgeno-Radiology
Russian Federation
Moscow
Russian Federation
Moscow
D. A. Kokontsev
Russian Scientific Center of Roentgeno-Radiology
Russian Federation
Moscow
Russian Federation
Moscow
T. S. Belle
Russian Scientific Center of Roentgeno-Radiology
Russian Federation
Moscow
Russian Federation
Moscow
References
1. Solodkiy V.A., Titova V.A. Automated contact radiation therapy – conditions for effective use in practical health care, Voprosy onkologii, 2016, Vol. 62, No. 5, pp. 688–693. (in Russian)
2. Titova V.A., Snigireva G.P., Petrovskiy V.Yu., Telysheva E.N. Modern approaches to radiotherapy of the oral cavity tumors, Sibirskiy onkologicheskiy zhurnal, 2016, Vol. 15, No. 5, pp. 47–54. (in Russian)
3. Titova V.A., Kokontsev D.A., Ivashin A.V., Khromov A.B. Contact radiation therapy on AGAT-BT apparatus using domestic imaging and planning systems, Vestnik RNTsRR, 2016, Vol. 16, No. 3, 9 p. (in Russian)
4. Pötter R., Haie-Meder C., Van Limbergen E., Barillot I., De Brabandere M., Dimopoulos J., Dumas I., Erickson B., Lang S., Nulens A., Petrow P., Rownd J., Kirisits C. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology, Radiother Oncol, 2006, Vol. 78, pp. 67–77.
5. Dimopoulos J.C.A., Petrow P., Tanderup K., Petric P., Berger D., Kirisits C., Pedersen E.M., van Limbergen E., Haie-Meder C., Pötter R. Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (IV): Basic principles and parameters for MR imaging within the frame of image based adaptive cervix cancer brachytherapy, Radiother Oncol, 2012, Vol. 103, pp. 113–122.
6. Chekhonadskiy V.N., Mar’ina L.A., Titova V.A., Kiseleva V.N. The effect of dose rate in the planning of intracavitary irradiation, Voprosy onkologii, 1998, Vol. 44, No. 5, pp. 551–555. (in Russian)
7. Stavitskiy R.V., Mil’shteyn R.S., Titova V.A. Distribution of doses near radiation sources in contact radiation therapy, Meditsinskaya radiologiya, 1984, No. 4, pp. 46–48. (in Russian)
8. Titova V.A., Sul’kin A.G., Sokolov V.G., Batner A.A. Comparison of methods for the formation of dose distributions for intracavitary gamma therapy, Meditsinskaya radiologiya, 1984, No. 5, pp. 67–71 (in Russian)
9. Tanderup K., Viswanathan A.N., Kirisits C., Frank S.J. Magnetic resonance image guided brachytherapy, Semin Radiat Oncol, 2014, Vol. 24, pp. 181–191.
10. Jastaniyah N., Yoshida K., Tanderup K., Lindegaard J.C., Sturdza A., Kirisits C., Šegedin B., Mahantshetty U., Rai B., Jürgenliemk-Schulz I.M., Haie-Meder C., Banerjee S., Pötter R. A volumetric analysis of GTVD and CTVHR as defined by the GEC ESTRO recommendations in FIGO stage IIB and IIIB cervical cancer patients treated with IGABT in a prospective multicentric trial (EMBRACE), Radiother Oncol, 2016, Vol. 120, pp. 404–411
11. Sumin A.V., Medvedkov A.M., Vasil’ev V.N., Smyslov A.YU., Rusetskiy S.S., Kokontsev A.A., Titova V.A., Kokontsev D.A. Verification of the operation of the scintillation multichannel clinical dosimeter MСD-04 in a collimated gamma radiation beam of a 60Co source, Meditsinskaya fizika, 2017, Vol. 75, No. 3, pp. 24–33. (in Russian)
12. Abalakin I.N., Nekrasova A.A., Sumin A.V., Titova V.A., Khmelinin D.I., Lomonosov A.M., Kheteev M.V. Klinicheskiy dozimetr-analizator dlya vnutripolostnykh in vivo izmereniy [Clinical dosimeteranalyzer for intracavitary in vivo measurements]. Patent RF na poleznuyu model’ no. 148494, 2014. 9 p.
Review
For citations:
Titova V.A., Kokontsev D.A., Belle T.S. CLINICAL PROBLEMS OF DIRECT DOSIMETRY (IN VIVO) IN CONTACT RADIATION THERAPY. Biomedical Photonics. 2018;7(2):19-24. (In Russ.) https://doi.org/10.24931/2413-9432-2018-7-2-19-24
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