Photodynamic therapy for metastatic breast cancer
Abstract
Results of treatment for cutaneous metastasis of breast cancer with photjdynamic therapy are represented. The study included 46 patients, the total number of treated cutaneous metastases was 535. For photodynamic therapy photosensitizer photolon given intravenously at a dose of 0.9–1.6 mg/kg body weight 3 h before treatment session (wave length 661±1 nm, плотность мощности 0,11–0,56 J/cm2), мощность на выходе волокна 0,3–2,0 Wt, light dose 50–600 J/cm2. Complete regression of metastasis was obtained in 33.6% of cases, partial – in 39.4%, stabilization – in 22.6%, progression of disease was in 4.3% of cases. The results show the perspectiveness of photodynamic therapy for metastasis as one of the step of treatment.
About the Authors
E. V. Horanskaya
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
M. A. Kaplan
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
V. N. Kapinous
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
E. V. Yaroslavtseva
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
I. S. Spichenkova
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
A. M. Shubina
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
O. V. Borgul
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
Ju. A. Ragulin
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
M. V. Taibova
Russian Medical Radiology Research Centre, Obninsk
Russian Federation
Russian Federation
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Review
For citations:
Horanskaya E.V., Kaplan M.A., Kapinous V.N., Yaroslavtseva E.V., Spichenkova I.S., Shubina A.M., Borgul O.V., Ragulin J.A., Taibova M.V. Photodynamic therapy for metastatic breast cancer. Photodynamic therapy and photodyagnosis. 2014;3(2):15-17. (In Russ.)
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