Sonodynamic therapy with photosensitizers and its combination with photodynamic therapy in treatment of malignant tumors
Abstract
The article reviews mechanisms of sonodynamic therapy with photosensitizers (ultrasound + photosensitizer) and combination of sonodynamic with photodynamic therapy (ultrasound + photosensitizer + light exposure) for treatment of malignant tumors. Efficacy of these methods with photosensitizers of different chemical structure in experimental study in vitro and in vivo on different tumor models and in clinical trials was assessed.
About the Authors
D. A. Zerkovskiy
N.N. Alexandrova Republic Research and Practical Centre of oncology and medical radiology, Minsk, Belarus
Belarus
Belarus
E. N. Alexandrova
N.N. Alexandrova Republic Research and Practical Centre of oncology and medical radiology, Minsk, Belarus
Belarus
Belarus
T. P. Laptsevich
N.N. Alexandrova Republic Research and Practical Centre of oncology and medical radiology, Minsk, Belarus
Belarus
Belarus
Ju. P. Istomin
N.N. Alexandrova Republic Research and Practical Centre of oncology and medical radiology, Minsk, Belarus
Belarus
Belarus
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Review
For citations:
Zerkovskiy D.A., Alexandrova E.N., Laptsevich T.P., Istomin J.P. Sonodynamic therapy with photosensitizers and its combination with photodynamic therapy in treatment of malignant tumors. Photodynamic therapy and photodyagnosis. 2014;3(2):18-23. (In Russ.)
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