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Photodynamic therapy of penile cancer

https://doi.org/10.24931/2413-9432-2020-9-1-42-46

Abstract

In this article we submit the case report of a patient with cT1N0M0 penile cancer diagnosis. The patient underwent two courses of photodynamic therapy (PDT) using Fotoditazin photosensitizer (PS) and ATKUS-2 diode laser. The PS was administered at a dose of 1 mg/kg of body weight 2 hours prior to the PDT session. The irradiation parameters were: 662 nm laser wavelength, 200 mW/cm2 power density and 250 J/cm2 energy density. In the presented clinical observation, we demonstrated that PDT is an effective and safe treatment method in patients with non-invasive penile cancer. The use of photodynamic therapy allowed preserving the physiological urination, sexual function and achieving a good cosmetic effect.

About the Authors

D. M. Yagudaev
Peoples’ Friendship University of Russia
Russian Federation
Moscow


G. P. Gens
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Moscow


Z. A. Kadyrov
Peoples’ Friendship University of Russia
Russian Federation
Moscow


A. V. Tikhonenko
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Moscow


N. A. Kalyagina
Prokhorov General Physics Institute of the Russian Academy of Sciences
Russian Federation
Moscow


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Review

For citations:


Yagudaev D.M., Gens G.P., Kadyrov Z.A., Tikhonenko A.V., Kalyagina N.A. Photodynamic therapy of penile cancer. Biomedical Photonics. 2020;9(1):42-46. https://doi.org/10.24931/2413-9432-2020-9-1-42-46

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