Long-term palliative treatment of patient with signet ring cell gastric cancer using endoscopic photodynamic therapy
Abstract
A case of multiple course of photodynamic therapy (PDT) in patient with gastric cancer T1N0M0. Morpholological diagnosis in this patient was signet ring cell cancer. For 8 years the patient underwent endoscopic organ-sparing treatment: PDT with Photohem (17 courses), electrocoagulation of tumor (3 sessions). The drug Photohem was introduced intravenously at dose of 3.0 mg/kg body weight for 48 h before PDT. The treatment result was only partial regression of gastric tumor, the maximal follow-up period with no endoscopic and morphological signs of tumor growth accounted for 8 months. However besides incomplete removal of gastric tumor and morphological type, for check-up examination 8 years after the onset of endoscopic treatment there were no features of regional and distant metastases according to chest and abdominal CT and US.
About the Authors
V. V. Sokolov
P.A. Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
E. V. Filonenko
P.A. Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
E. S. Karpova
P.A. Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Sokolov V.V., Filonenko E.V., Karpova E.S. Long-term palliative treatment of patient with signet ring cell gastric cancer using endoscopic photodynamic therapy. Photodynamic therapy and photodyagnosis. 2014;3(3):34-36. (In Russ.)
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