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Photodynamic therapy of a patient with basal cell skin cancer of the ear stage T3N0M0 (clinical case)

https://doi.org/10.24931/2413-9432-2021-10-4-68-70

Abstract

The article presents a clinical observation. The patient, 72 years old, applied to the MNII them. P.A. Herzen with complaints about the presence of an ulcerated tumor of the left ear. After further examination, a diagnosis was made - basal cell carcinoma of the ear skin with spread to the skin of the parotid region T3N0M0. On July 9, 2021, the patient underwent a course of photodynamic therapy (PDT) using a photosensitizer based on chlorin e6 and a diode laser with a wavelength of 662 nm. After one course of PDT, complete regression of the tumor was recorded.

About the Authors

E. V. Filonenko
P.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of the Russian Federation
Russian Federation

Moscow



N. I. Grigoryevykh
P.A. Herzen Moscow Oncology Research Center – branch of FSBI NMRRC of the Ministry of Health of the Russian Federation
Russian Federation

Moscow



V. I. Ivanova-Radkevich
Peoples’ Friendship University of Russia (RUDN University)
Russian Federation

Moscow



References

1. Sokolov  V.V., Chissov  V. I., Filonenko E.V. et al. Photodynamic therapy of cancer with the photosensitizer PHOTOGEM, Proceedings of SPIE  – The  International Society for Optical Engineering, 1995, vol. 2325, рр. 367–374. doi: 10.1117/12.199169

2. Sokolov V.V., Chissov V. I., Yakubovskya R. I. et al. Photodynamic therapy (PDT) of malignant tumors by photosensitzer photosens: results of 45 clinical cases. Proceedings of SPIE – The International Society for Optical Engineering, 1996, vol. 2625, рр. 281–287.

3. Sokolov V.V., Chissov V. I., Filonenko E.V. et al. First clinical results with a new drug for PDT, Proceedings of SPIE – The International Society for Optical Engineering, 1995, vol. 2325, рр. 364–366. doi: 10.1117/12.199168

4. Filonenko E.V. The history of development of fluorescence diagnosis and photodynamic therapy and their capabilities in oncology, Russian Journal of General Chemistry, 2015, vol. 85 (1), рр. 211–216. doi: 10.1134/S1070363215010399


Review

For citations:


Filonenko E.V., Grigoryevykh N.I., Ivanova-Radkevich V.I. Photodynamic therapy of a patient with basal cell skin cancer of the ear stage T3N0M0 (clinical case). Biomedical Photonics. 2021;10(4):68-70. https://doi.org/10.24931/2413-9432-2021-10-4-68-70

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ISSN 2413-9432 (Print)