Spectral luminescent properties of bacteriochlorin and aluminum phthalocyanine nanoparticles as hydroxyapatite implant surface coating
https://doi.org/10.24931/2413-9432-2016-5-2-4-12
Abstract
The development and the spectral research of unique coating as crystalline nanoparticles of IR photosensitizers were performed for the creation of hydroxyapatite implants with photobactericidal properties. It has been proved that by the interaction of nanoparticles covering implant with the polar solvent, which simulates the interaction of the implant with the biocomponents in vivo (fast proliferating and with immunocompetent cells), photosensitizers nanoparticles change the spectroscopic properties, becoming fluorescent and phototoxic. Thus, the developed coating based on crystalline photosensitizer nanoparticles with studied specific properties should have antibacterial, anti-inflammatory effect by the photodynamic treatment in the near implant area. This research opens the prospect of the local prevention of inflammatory and autoimmune reactions in the area of implantation. The results of the study suggest a promising this technology in order to create implants with photobactericidal properties.
About the Authors
Yu. S. Maklygina
General Physics Institute of the Russian Academy of Sciences
Russian Federation
Moscow
Russian Federation
Moscow
A. S. Sharova
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Russian Federation
Moscow
Russian Federation
Moscow
B. Kundu
Bioceramics and Coating Division, CSIR-Central Glass and Ceramic Research Institute
India
Kolkata
India
Kolkata
V. K. Balla
Bioceramics and Coating Division, CSIR-Central Glass and Ceramic Research Institute
India
Kolkata
India
Kolkata
R. Steiner
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute);
The Institute for Laser Technology in Medicine and Measurement Technique
Germany
Germany
Moscow;
Ulm
V. B. Loschenov
General Physics Institute of the Russian Academy of Sciences;
National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Maklygina Yu.S., Sharova A.S., Kundu B., Balla V.K., Steiner R., Loschenov V.B. Spectral luminescent properties of bacteriochlorin and aluminum phthalocyanine nanoparticles as hydroxyapatite implant surface coating. Biomedical Photonics. 2016;5(2):4-12. https://doi.org/10.24931/2413-9432-2016-5-2-4-12
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