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The possibilities of fluorescence study for pre-histological endoscopic diagnosis of malignant polyp adenoma (case report)

Abstract

The results of fluorescence diagnosis with alasens in patient with sigmoid polyps are represented in the article. Fluorescence study gave a suspicion of malignant transformation in one of polyps. According to morphological data there was a well-differentiated colon adenocarcinoma with underlying tubular adenoma in suspicious region. Thus, fluorescence data showed malignant tumor prior to routine histological study, which was misdiagnosed for routine colonoscopy and biopsy without fluorescence diagnosis.

 

About the Authors

А. А. Sokolov
Russian Medical Academy of Post-Graduate Education, Moscow
Russian Federation


А. А. Razgivina
Russian Medical Academy of Post-Graduate Education, Moscow
Russian Federation


А. V. Volova
Russian Medical Academy of Post-Graduate Education, Moscow
Russian Federation


References

1. Гребнев А.Л., Шептулин А.А. Трудности дифференциальной диагностики между доброкачественными язвами, малигнизацией язвы и инфильтративно-язвенной формой рака желудка // Пробл. гастрэнтерол. – 1991. – № 1. – С. 71–77.

2. Stepp H., Sroka R., Baumgartner R. Fluorescence endoscopy of gastrointestinal diseases: basic principles, techniques and clinical experience // Endoscopy. – 1998. – 30 (4). – Р. 379–386.

3. Baumgartner R., Huber R.M., Schulz H., et al. Inhalation of 5-aminolevulinic acid: a new technique for fluorescence detection of early stage lung cancer // J Photochem Photobiol B. – 1996. – 36. – Р. 169–174.

4. Hautmann H., Pichler J.P., Stepp H. et al. In-vivo kinetics of inhaled 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in bronchial tissue // Respir. Res. – 2007. – 19. – Р. 8–33.


Review

For citations:


Sokolov А.А., Razgivina А.А., Volova А.V. The possibilities of fluorescence study for pre-histological endoscopic diagnosis of malignant polyp adenoma (case report). Photodynamic therapy and photodyagnosis. 2013;2(1):52-54. (In Russ.)

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ISSN 2413-9432 (Print)