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PHOTODYNAMIC THERAPY OF RESIDUAL LARYNGEAL TUMOR AFTER EBRT (CASE REPORT)

https://doi.org/10.24931/2413-9432-2017-6-3-45-48

Abstract

A case of successful photodynamic therapy of residual laryngeal tumor after external beam radiotherapy (EBRT) is reported. The female patient with diagnosis of laryngeal cancer T1N0M0 underwent a course of EBRT on larynx, fraction dose = 2 Gy, 5 fractions per week, total radiation dose = 60 Gy. One month after EBRT the continued growth of residual tumor in the left vocal fold was diagnosed. The patient had 4 courses of photodynamic therapy with photosensitizer fotoditazin at a dose of 100 mg combined with electroresection of residual laryngeal tumor. The control video-assisted laryngoscopy 1 month after the 4th course of photodynamic therapy showed that larynx was flexible, vocal function was fully restored, tumor of the left vocal fold wasn’t detected. Non-recurrence follow-up period is 10 month. The patient is under follow-up.

About the Authors

V. M. Legostaev
Rostov Research Institute of Oncology.
Russian Federation
Rostov-on-Don.


G. M. Maldonado
Rostov Research Institute of Oncology.
Russian Federation
Rostov-on-Don.


E. F. Islamova
Rostov Research Institute of Oncology.
Russian Federation
Rostov-on-Don.


References

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Review

For citations:


Legostaev V.M., Maldonado G.M., Islamova E.F. PHOTODYNAMIC THERAPY OF RESIDUAL LARYNGEAL TUMOR AFTER EBRT (CASE REPORT). Biomedical Photonics. 2017;6(3):45-48. (In Russ.) https://doi.org/10.24931/2413-9432-2017-6-3-45-48

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ISSN 2413-9432 (Print)