Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma
Abstract
The case of successful intraoperative fluorescence diagnosis (IOFD) for removal of cervical and thoracic ependymoma performed in P.A. Herzen MCRI is reported. For FD we used the Alasens (Research Institute of Organic Semi-Finished Products and Dyes). The drug solution was given per os at a dose of 20 mg/kg body weight 2.5 h before surgery. IOFD was per-formed 3 h after intake of photosensitizer. For fluorescence diagnosis there was average in-tensity of fluorescence in tumor and no fluorescence in normal spinal tissues. The extent of surgery was determined according to results of IOFD. The control MRI of cervical and supeior thoracic spine with contrast enhancement and follow-up confirmed definitive removal of tumor and showed no postoperative complications.
About the Authors
A. M. Zaytcev
P.A.Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
M. I. Kurzhupov
P.A.Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
Ju. V. Kushelj
N.N. Burdenko Research Institute of Neurosurgery, Moscow
Russian Federation
Russian Federation
E. V. Filonenko
P.A.Herzen Moscow Cancer Research Institute, Moscow
Russian Federation
Russian Federation
V. I. Ivanova-Radkevich
Peoples Friendship University of Russia, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Zaytcev A.M., Kurzhupov M.I., Kushelj J.V., Filonenko E.V., Ivanova-Radkevich V.I. Intraoperative fluorescence diagnosis for removal of cervical and thoracic ependymoma. Photodynamic therapy and photodyagnosis. 2014;3(2):24-27. (In Russ.)
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