Photodynamic therapy for recurrent basal cell skin carcinoma of the parietal region after radiotherapy
https://doi.org/10.24931/2413-9432-2016-5-2-38-40
Abstract
The results of the clinical observation of patient with recurrent basal cell skin carcinoma of the parietal region occurred in 4 years after radiation therapy are represented. The patient underwent photodynamic therapy (PDT) using photosensitizer fotoditazin at a dose of 1.0 mg/kg; the laser power density was 0.45 W/cm2 , the laser energy density – 300 J/cm2 . Tolerability of the treatment was satisfactory. One year after treatment there was a cosmetically satisfying soft normotrophic scar with no attachment to underlying tissues in the site of the treatment of basal cell carcinoma. According to cytological study tumor cells were not detected. For five-year follow-up there was no recurrence.
About the Author
O. V. Matveeva
Sechenov First Moscow State Medical University
Russian Federation
Moscow
Russian Federation
Moscow
References
1. Filonenko E.V. Fluorescence diagnosis and photodynamic therapy – justification of use and opportunities in oncology, Fotodinamicheskaya terapiya i fotodiagnostika, 2014, No. 1, pp. 3–7. (in Russian)
2. Calixto G.M., Bernegossi J., De Freitas L.M., Fontana C.R., Chorilli M. Nanotechnology-Based Drug Delivery Systems for Photodynamic Therapy of Cancer: A Review, Molecules, 2016, Vol. 21, No. 3, p. 342.
3. Kaviani A., Ataie-Fashtami L., Fateh M., Sheikhbahaee N., Ghodsi M., Zand N., Djavid G.E. Photodynamic therapy of head and neck basal cell carcinoma according to different clinicopathologic features, Lasers in Surgery and Medicine, 2005, Vol. 36, No. 5, pp. 377-382.
4. Kapinus V.K., Romanko Yu.S., Kaplan M.A., Ponomarev G.V., Sokol N.I. Efficiency of fluorescence diagnosis and photodynamic therapy with photosensitizer fotoditazin in patients with skin cancer), Rossiiskii bioterapevticheskii zhurnal, 2005, T. 4, No. 3, pp. 69–75. (in Russian)
5. Molochkova Yu.V., Kuntsevich Zh.S., Sukhova T.E., Dibirova S.D., Galkin V.N., Ivanov S.A., Romanko Yu.S. Photodynamic therapy of typical and atypical keratoacanthoma, Al'manakh klinicheskoy meditsiny, 2016, Т. 44, No. 1, pp. 64–70. (in Russian)
6. Katsalap S.N., Romanko Yu.S. The choice of photodynamic therapy against recurrent basal cell carcinoma, Vestnik esteticheskoy meditsiny, 2012, T. 11, No. 1, pp. 44–48. (in Russian)
Review
For citations:
Matveeva O.V. Photodynamic therapy for recurrent basal cell skin carcinoma of the parietal region after radiotherapy. Biomedical Photonics. 2016;5(2):38-40. https://doi.org/10.24931/2413-9432-2016-5-2-38-40
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