Radiation dosimetry in the health and medicine field is crucial to ensure there is no unnecessary ionizing radiation exposure to patients and personnel. While various types of semiconductor dosimeters are available, photodiode sensors are seen as a reliable and cost-effective immediate dosimeter. This study investigates the capabilities of a monolithic photodiode with an on-chip trans-impedance amplifier as a dosimeter in diagnostic radiology. A photodiode sensor covered with black insulation tape is irradiated with the diagnostic x-ray of potential in range between 40 to 90 kV with constant tube current-time product of 50 mAs at 60 cm source-to-detector distance (SDD). Exposures of different tube current at the range of 10 to 250 mA with a constant tube voltage of 70 kVp at the same setup are made. The photodiode sensor connected to the electrometer gives out readings in the millivolt (mV), and the output of the photodiode and semiconductor detector is recorded. The photodiode’s energy dependency, reproducibility, dose response, and distance dependency were evaluated as the capabilities of the photodiode to be used as a dosimeter. For energy dependency, it shows a linearity of 0.9458, while the response to increasing tube current with a constant tube voltage shows the R2 of 0.912. The photodiode shows good dependency on the tube voltage and tube current. Other than that, it also showed a linear coefficient of 0.5138 for distance dependence which is considered as a good linearity fit value for a photodiode as initial performance. However, its reproducibility is poor due to its large capacitance. This monolithic photodiode with an on-chip trans-impedance amplifier has demonstrated good results for energy dependency but poor results for reproducibility. However, the photodiode can be improvised in the future to ensure it is suitable as a dosimeter.

The article is devoted to the problem of voice rehabilitation of patients after laryngectomy. Modern possibilities of repairing laryngeal vocal function, methods for extending the lifetime of voice prostheses are considered. The author’s method of prevention of infection of vocal prostheses using the antimicrobial photodynamic therapy (PDT) with chlorin-type photosensitizer Radagel is presented. Performing antimicrobial PDT of vocal prostheses increased the average operating time to 11.9 months compared to the control group (6.8 months), where a monthly dose of 150 mg of fluconazole was used for prevention. The method developed by the authors makes it possible to significantly extend the lifetime of vocal prostheses, is devoid of adverse events, is well tolerated by patients.

To improve the quality and effectiveness of medical care for patients with inflammatory periodontal diseases, it is necessary to search for new approaches in both diagnosis and treatment. The aim of our study is to determine the effect of the diode laser on the pathogenic microflora of periodontal pockets and root canals in patients with endo-periodontal lesions (EPL). We carried out a comparative assessment of the bacterial contents of the root canals and periodontal pockets by polymerase chain reaction (PCR) before and after treatment with a diode laser (Doctor Smile Simpler, wavelength 980 nm) for 54 patients with EPL. The control group consisted of 56 patients who were treated according to the generally accepted method, including professional oral hygiene, endodontic treatment, and curettage of periodontal pockets. Evaluation criteria were a qualitative assessment of the content of periodontopathogens in the root canal and periodontal pocket before and after and treatment. As a result of our study, we found a statistically significant (p<0.01) reduction in the colonization of periodontal pockets and root canals in patients with EPL after laser decontamination. The high technological effectiveness of the methods used in combination with the low risk of complications at the stages of endodontic and periodontological treatment provides an antibacterial effect and reduces the duration of inflammation. The results of treatment of patients using a diode laser give reason to recommend their use in the dental practice.

This review highlights the possibilities of photodynamic therapy (PDT) using drugs based on chlorin e6, aluminum phthalocyanine, methylene blue as photosensitizers for bacterial and fungal pathologies. This method was developed initially to treat tumor diseases, where it had shown its high efficiency and safety. Now photodynamic therapy is actively used in the treatment of cancers of the skin, bronchi, stomach, cervix, larynx, or other regions. However, numerous studies have been carried out for the entire existence of the method, demonstrating new possibilities of its application. This review highlights a number of studies in which the efficacy and safety of antimicrobial and antimycotic PDT were studied in vivo and in vitro. It has been proven to have a positive effect on the reparative processes in the wound. An experimental study was carried out to study the effectiveness of photodynamic therapy in the treatment of peritonitis in mice. Demonstrated anti-inflammatory potential in the treatment of autoimmune diseases.

Recent years are characterized by the active development and advancement in clinical practice of the method of photodynamic therapy (PDT). PDT shows high effectiveness in the treatment of skin tumors, digestive, nervous, respiratory systems, in gynecology, ophthalmology. Antimicrobial PDT is successfully used in the treatment of purulent wounds and infectious diseases. One of the most actively developing applications of antitumor PDT is the treatment of maxillofacial tumors.

The study assessed the organization of medical care for patients with malignancies of the maxillofacial region (MNMR) in the Penza region and the provision of oncologists, maxillofacial surgeons specializing in the treatment of tumor pathology. In the course of the study, the incidence of MNMR of the population of the Penza region and the gender and age structure were determined. The shortcomings of the organization of medical care for patients with MNMR are indicated.